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Product NameAc-WEHD-CHO
CatalogCASP-004A
SequenceAc-Trp-Glu-His-Asp-CHO
Size1mg
Price$25.00
CxHxNxOxSxClxC28H33N7O9
MV611.61
DescriptionVery potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
Remarks
Literature ReferenceT.A. Rano et al., Chem. Biol., 4, 149 (1997); M. Garcia-Calvo et al., J. Bio. Chem., 273, 32608 (1998)
CAS[189275-71-6]
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