Loading... Please wait...

Call 408-734-3800 / Toll Free 877-272-7241

Menu

CANC-022A

PD-L1 binding peptide WL12

cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt)
(Thioether bridge: Cys14-Ac-Tyr)

$265.00
Quantity:

Product Description

WL12 peptide selectively binds to programmed death ligand 1 (PD-L1), an immune checkpoint protein that is overexpressed in many cancer cell lines. Tumor PD-L1 expression contributes to immune system depression and is indicative of a tumor’s response to PD-L1 and PD-1.

SEQUENCE: cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt)
(Thioether bridge: Cys14-Ac-Tyr)

ONE-LETTER SEQUENCE: cyclo(AcY-MeANPHL-Hyp-WSW(Me)-MeNle-MeNle-OC)-G-NH2 (trifluoroacetate salt)
(Thioether bridge: C14-Ac-Y)

MOLECULAR FORMULA: C91H128N22O20S

MOLECULAR WEIGHT: 1882.19

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Cancer, Apoptosis

CATEGORY: Apoposis Related Peptides

REFERENCES:
Chatterjee, Samit, et al. "Rapid PD-L1 detection in tumors with PET using a highly specific peptide." Biochemical and biophysical research communications 483.1 (2017): 258-263.

cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt)
(Thioether bridge: Cys14-Ac-Tyr)

cyclo(AcTyr-MeAla-Asn-Pro-His-Leu-Hyp-Trp-Ser-Trp(Me)-MeNle-MeNle-Orn-Cys)-Gly-NH2 (trifluoroacetate salt)
(Thioether bridge: Cys14-Ac-Tyr)

Product Reviews

This product hasn't received any reviews yet. Be the first to review this product!

Customers also viewed

Related Products

Click the button below to add the PD-L1 binding peptide WL12 to your wish list.