CPC Scientific offers a variety of generic peptides used as active pharmaceutical ingredients (APIs). These generic peptides are utilized to treat a variety of diseases including cancer, diabetes, obesity, and multiple sclerosis. Our GMP manufacturing facility employs a rigorous quality and EHS system to insure global compliance, including the stringent requirements of the United States, European Union, China, and Japan. In addition, we fully support our pharmaceutical customers with required regulatory documentation including Drug Master Files (DMFs). Below is a listing of generic peptides that we currently provide.
AVAILABLE GENERIC PEPTIDES:
|API Name||Structure / Sequence||Indication||DMF Schedule|
|Leuprolide Acetate||pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt||Hormone-Responsive Cancers||US FDA 5/2015; CFDA: Approved 2009|
|Terlipressin Acetate||H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (disulfide bridge)||Cardiovascular (blood pressure regulation)||CFDA: 12/2016|
|Triptorelin Acetate||pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2||Assisted Reproduction, Cancer||CFDA: 3/2014|
|Exenatide Acetate||H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2||Diabetes||US FDA: 7/2017; CFDA: 8/2015|
|Liraglutide Acetate||H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH||Diabetes (type II)||US FDA: 7/2017|
|Buserelin Acetate||pGlu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt||Prostate Cancer, Breast Cancer||CFDA: 6/2016|
|Cetrorelix Acetate||Ac-D-Nal-D-Cpa-D-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2||Assisted Reproduction. Prostate and Breast
Hormone therapy drug used to treat prostate cancer. Leuprolide is a nonapeptide GnRH (LHRH) analog that stops the pituitary gland from producing luteinizing hormone. This action leads to a reduction in testosterone levels, which may help to shrink the tumor or slow its growth. LEARN MORE ►
Prevents the production of certain types of hormones in the body. Triptorelin is a decapeptide GnRH (LHRH) agonist used to treat men with prostate cancer, women who have uterine fibroids or endometriosis, and boys and girls when puberty occurs prematurely.
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Decreases blood flow to the gastrointestinal system and can help reduce gastrointestinal bleeding caused by high blood pressure in the liver or swollen blood vessels in the esophagus. Terlipressin is an analog of the peptide hormone, vasopressin, used as a vasoactive drug in the management of hypotension. LEARN MORE ►
A glucagon-like peptide (GLP)-1 receptor agonist used for the treatment of type 2 diabetes and obesity. It works by increasing the amount of insulin produced by the body. It also helps decrease sugar levels produced by the liver and absorbed by the intestines. LEARN MORE ►
Buserelin is a gonadotropin-releasing hormone agonist (GnRH agonist). Interactions of buserelin with GnRH causes immediate release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by gonadotrophes. LEARN MORE ►
Exenatide is an injectable drug that reduces the level of glucose in the blood and is used to treat type 2 diabetes. It is a 39-amino acid peptide that resembles and acts like GLP-1, which the action of glucagon, and reduces appetite.Glatiramer Acetate. Glatiramer is an immunomodulator drug used to treat multiple sclerosis in cases when there have been relapses followed by periods of recovery. It is a random polymer of four amino acids found in myelin basic protein that works by preventing the body from damaging nerve cells. LEARN MORE ►
A long-acting octapeptide with pharmacologic actions mimicking those of the natural hormone somatostatin. Octreotide reduces blood levels of growth hormone (GH) and insulin-like growth factor (IGF-1) in acromegaly patients. Octreotide is also used to control symptoms such as diarrhea or flushing in patients with carcinoid tumors, pancreatic islet cell tumors, gastrinoma, or vasoactive intestinal peptide-secreting tumors (VIPomas).
Glucagon, a single-chain polypeptide containing 29 amino acid residues, is a peptide hormone that increases blood glucose concentration and is used in the treatment of hypoglycemia. It acts only on liver glycogen, converting it to glucose. Glucagon relaxes smooth muscle of the stomach, duodenum, small bowel, and colon.
Bivalirudin is a 20 residue peptide (direct thrombin inhibitor) that reversibly inhibits thrombin. It is used in patients who are having certain heart and blood vessel procedures, such as coronary angioplasty. Bivalirudin decreases the blood’s clotting ability, which helps prevent harmful blockages from forming in blood vessels.
A cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Eptifibatide keeps the platelets in the blood from coagulating (clotting) to prevent blood clots or heart attack for those with severe chest pain or other conditions, and for those undergoing angioplasty to open blocked arteries.
Developing peptides to your exact specifications. Don’t see the generic API that you are looking for? Please let us know so that we can discuss peptides that will meet your particular needs. We are your peptide partners from concept to commercial.