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Terlipressin Acetate

Terlipressin Acetateterlipressin generic peptide for the treatment of gastrointestinal bleeding

 

Terlipressin is a cyclized dodecamer peptide (H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2, disulfide bridge) that attenuates blood flow to the gastrointestinal tract and is consequently used to treat gastrointestinal bleeding. The peptide has a similar sequence to vasopressin, also known as arginine vasopressin, because most species have an arginine residue at position eight (H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2disulfide bridge). In addition to our generic product, CPC Scientific provides [Arg8] Vasopressin and analogs [Lys8] as research-grade ready-to-ship catalog peptides. 
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SEQUENCE:  H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH(disulfide bridge)
MOLECULAR FORMULA:  C52H74N16O15S2
MOLECULAR WEIGHT:  1227.37
CAS REGISTRY NUMBER:  [14636-12-5]
SYNONYMS:  Teripress, Glypressin
CLINICAL AREA:  Cardiovascular (blood pressure regulation)
DMF SCHEDULE:  CFDA: 12/2016