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Degarelix Acetate

degarelix generic API

Degarelix is a peptide used in hormonal therapy to treat prostate cancer. Degarelix binds to gonadotropin-releasing hormone (GnRH) receptors of the pituitary gland and prevents GnRH from binding. The binding of degarelix to GnRH receptors causes an immediate and profound reduction in luteinizing hormone (LH), follicle-stimulating hormone (FSH) and in turn, testosterone suppression.

 

PRODUCT NAME:  Degarelix Acetate
SEQUENCE:  Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2
MOLECULAR FORMULA:  C82H103ClN18O16
MOLECULAR WEIGHT:  1632.26
CAS REGISTRY NUMBER:  [214766-78-6]
SYNONYMS:  Firmagon, FE200486
CLINICAL AREA:  Prostate Cancer
DMF SCHEDULE:  CFDA: 6/2016
MANUFACTURER:  CPC Scientific Inc.