Leuprolide is a nonapeptide GnRH (LHRH) analog (pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt) that stops the pituitary gland from producing luteinizing hormone. This action leads to a reduction in testosterone levels, which may help to shrink the tumor or slow its growth.
Leuprolide may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in In Vitro Fertilization (IVF). It is considered a possible treatment for paraphilias. Leuprolide also has been tested as a treatment for reducing sexual urges in pedophiles and other cases of paraphilia.
|PRODUCT NAME:||Leuprolide Acetate|
|CAS REGISTRY NUMBER:||[53714-56-0]|
|CLINICAL AREA:||Hormone-Responsive Cancers|
|DMF SCHEDULE:||US FDA 5/2015; CFDA: Approved 2009|
|MANUFACTURER:||CPC Scientific Inc.|
|FDA REGISTRATION #:||29355|
|TYPE:||Ⅱ (Drug Substance, Drug Substance Intermediate, and Material Used in Their Preparation, or Drug Product)|